antacids they are used to treat acid reflux which causes heartburn, indigestion and stomach ailments. They provide rapid relief from heartburn, which is a major symptom of gastroesophageal reflux disease and indigestion. Treatment with antacids is symptomatic and is usually recommended for minor symptoms. Antacids include magnesium carbonate, aluminum hydroxide and magnesium trisilicate. Some people have reported allergic reactions to antacids. Antacids with magnesium can cause diarrhea, while those containing calcium and aluminum can cause constipation. Long-term use can cause kidney stones and may increase the risk of contracting osteoporosis. The best known antacid brands are Alka Seltzer, Gelusil, Milk of Magnesia, Maalox, Gaviscon, Mylanta, Rolaids and Tums.
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Market taxonomy of antacid drugs – Formulation, drugs and demographic data
The market for antacid drugs is classified in various ways, for example by formulation, drugs and demographic data. Based on the formulation, the market for antacids is classified as tablets, capsules, suspensions and drops. Based on the demographic market, antacids are classified as pediatric products and adult products. Based on the drug, the market for antacid drugs is classified as histamine-2 (H2) blockers, a proton pump inhibitor and pro-motility agents. Examples of H2 blocker include nizatidine, ranitidine, cimetidine and famotidine. Proton pump inhibitors used for acid reflux include Rabeprazole, Esomeprazole, Lansoprazole, Pantoprazole and Omeprazole. The pro motility agents stimulate the muscles of the gastrointestinal tract and strengthen the lower esophageal sphincter and reduce reflux in the esophagus. Metoclopramide is used to treat heartburn associated with GERD.
Increasing incidence of acid reflux in North America that feeds the growth of the antacid drug market
The increase in the self-medication trend consequently fuels the demand for OTC digestive products for the treatment of gastrointestinal discomfort. Antacids are used to neutralize acidity and therefore, are expected to cause an unrestrained increase in demand for the same in North America due to the increase in the incidence of gastroesophageal reflux disease (GERD) in the area. According to a study by the American Gastroenterological Association and published in the International Foundation for Functional in February 2016, about one third of the population in the United States suffers from GERD. According to a study published in the National Center for Biotechnology Information (NCBI) in June 2014, the prevalence range of GERD was 18.1% -27.8% in North America, 8.7% -33.1% in the Middle East , 8.8% -25.9% in Europe, 2.5% -7.8% in East Asia and 11.6% in Australia. The increase in the prevalence of GERD creates a favorable environmental growth in the antacid drug market.
Various companies produce antacids and other products for indigestion. Some of these are GlaxoSmithKline plc, Dabur India Limited, Abbott Laboratories and Pfizer, Inc. Sun Pharma launched an ayurvedic digestive remedy called Pepmelt to compete with popular antacids such as Eno (GSK consumer healthcare), Digene (Abbott India), Pudin Hara (Dabur), and Gelusil (Pfizer).