The new biodegradable nanofibre bandage allows faster healing (Representational Image) & nbsp | & nbspPhoto Credit: & nbspGetty Images
Moscow: An international team of scientists has developed a new bandage with a strong antibacterial effect and which can be maintained for long periods of time without needing to be changed, thus accelerating the regrowth of the skin and reducing the risk of infection. The new dressing material has great potential for future application in wound healing, does not require changes and can literally be overlapped as it degrades, Sputnik news agency reported.
The traditional use of an antiseptic in the treatment of wounds, consisting in washing the affected area with a solution and in the use of gauze to increase the outflow of liquids, repeated several times.
However, such treatment, in particular the use of antibiotics kill not only dangerous bacteria but also useful bacteria. And when the dressings are changed, the fragile area undergoing healing is disturbed, causing severe pain to the patients.
But according to scientists from the MISiS National University of Science and Technology, based in Moscow, and the Brno University of Technology of the Czech Republic, the new biocompatible medication material can act locally in the area of inflammation. As the material slowly releases their antibiotic, the dressings gradually dissolve on the skin.
The material was made of polypropylactone nanofibers – a biocompatible and bioabsorbable material – and attacked gentamicin, a broad-spectrum antibiotic, to the fibers.
"What we have discovered is that the action has been prolonged: we observed a significant decrease in the number of bacteria even 48 hours after the application of the material," said MISiS 'Elizaveta Permyakova.
"Usually, surfaces with an antibacterial effect meet their potential within the first day or even the first hours of use," explained Permyakova. In the study, reported in the academic journal Materials and Design, the team conducted experiments using three strains of E. coli bacteria, with strains showing different levels of antibiotic resistance, but nevertheless effectively fought against dressing.
The new material is potentially applicable not only for skin care treatment but for the treatment of inflammatory bone diseases such as osteoporosis and osteomyelitis, the report noted.